Angelman Syndrome is a rare genetic disorder caused by the loss of function of the UBE3A gene on chromosome 15. It primarily affects the nervous system, leading to developmental delays, intellectual disability, speech impairment, and motor difficulties such as ataxia and seizures. Individuals with Angelman Syndrome often exhibit a happy, excitable demeanor, frequent laughter, and a strong social connection. Our children laugh and love hard!

Support & Resources

This section goes through everything from therapies, standards of care, entitlements, and managing the complexities of living with Angelman syndrome.

Understanding Angelman

For professionals, parents or people who are interested to learn more. This section explains the syndromes genetic variants, common traits and diagnostic testing approaches.